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Daniela Chirio

Associate Professor

Contacts

At

  • Department of Drug Science and Technology
  • Dipartimento di Scienza e Tecnologia del Farmaco
  • Corsi di studio in
    Farmacia - Chimica e tecnologia farmaceutiche
  • Corso di Laurea in Tecniche Erboristiche

Curriculum vitae

  • Curriculum Vitae (27.7 KB)

    • Research products

    All my research products

    Selected research products

    Naked and Decorated Nanoparticles Containing H2S-Releasing Doxorubicin: Preparation, Characterization and Assessment of Their Antitumoral Efficiency on Various Resistant Tumor Cells
    2022-01-01 Elena PEIRA; Daniela Chirio; Simona Sapino; Konstantin CHEGAEV; Giulia Chindamo; IRIS CHIARA SALAROGLIO; Chiara Riganti; Marina GALLARATE https://iris.unito.it/handle/2318/1885286

    Doxorubicin-Loaded Lipid Nanoparticles Coated with Calcium Phosphate as a Potential Tool in Human and Canine Osteosarcoma Therapy
    2022-01-01 Chirio, Daniela; Sapino, Simona; Chindamo, Giulia; Peira, Elena; Vercelli, Cristina; Riganti, Chiara; Manzoli, Maela; Gambino, Graziana; Re, Giovanni; Gallarate, Marina https://iris.unito.it/handle/2318/1873043

    Nanocarriers in Veterinary Medicine: A Challenge for Improving Osteosarcoma Conventional Treatments
    2022-01-01 Sapino S.; Chindamo G.; Chirio D.; Morel S.; Peira E.; Vercelli C.; Gallarate M. https://iris.unito.it/handle/2318/1885368

    Recent advances in nanosystems and strategies for vaginal delivery of antimicrobials
    2021-01-01 Chindamo G.; Sapino S.; Peira E.; Chirio D.; Gallarate M. https://iris.unito.it/handle/2318/1775029

    Osteomyelitis: Focus on Conventional Treatments and Innovative Drug Delivery Systems
    2021-01-01 Gallarate, Marina; Chirio, Daniela; Chindamo, Giulia; Peira, Elena; Sapino, Simona https://iris.unito.it/handle/2318/1816334

    A new bevacizumab carrier for intravitreal administration: Focus on stability
    2021-01-01 Chirio D.; Peira E.; Sapino S.; Chindamo G.; Oliaro-bosso S.; Adinolfi S.; Dianzani C.; Baratta F.; Gallarate M. https://iris.unito.it/handle/2318/1795350

    Developing actively targeted nanoparticles to fight cancer: Focus on italian research
    2021-01-01 Argenziano M.; Arpicco S.; Brusa P.; Cavalli R.; Chirio D.; Dosio F.; Gallarate M.; Peira E.; Stella B.; Ugazio E. https://iris.unito.it/handle/2318/1816443

    Assessment of in‐situ gelling microemulsion systems upon temperature and dilution condition for corneal delivery of bevacizumab
    2021-01-01 Peira E.; Chindamo G.; Chirio D.; Sapino S.; Oliaro-bosso S.; Rebba E.; Ivanchenko P.; Gallarate M. https://iris.unito.it/handle/2318/1795299

    Calcium Phosphate-Coated Lipid Nanoparticles as a Potential Tool in Bone Diseases Therapy
    2021-01-01 Sapino, Simona; Chindamo, Giulia; Chirio, Daniela; Manzoli, Maela; Peira, Elena; Riganti, Chiara; Gallarate, Marina https://iris.unito.it/handle/2318/1816356

    Bone diseases: Current approach and future perspectives in drug delivery systems for bone targeted therapeutics
    2020-01-01 Chindamo G.; Sapino S.; Peira E.; Chirio D.; Gonzalez M.C.; Gallarate M. https://iris.unito.it/handle/2318/1740158

    Curcumin-loaded solid lipid nanoparticles bypass p-glycoprotein mediated doxorubicin resistance in triple negative breast cancer cells
    2020-01-01 Abd-Ellatef G.-E.F.; Gazzano E.; Chirio D.; Hamed A.R.; Belisario D.C.; Zuddas C.; Peira E.; Rolando B.; Kopecka J.; Marie M.A.S.; Sapino S.; Fahmy S.R.; Gallarate M.; Abdel-Hamid A.-H.Z.; Riganti C. https://iris.unito.it/handle/2318/1740386

    Ocular Drug Delivery: A Special Focus on the Thermosensitive Approach
    2019-01-01 Sapino, Simona; Chirio, Daniela; Peira, Elena; Abellán Rubio, Elena; Brunella, Valentina; Jadhav, Sushilkumar A; Chindamo, Giulia; Gallarate, Marina https://iris.unito.it/handle/2318/1707648

    Poly (N-isopropylacrylamide) based hydrogels as novel precipitation and stabilization media for solid lipid nanoparticles (SLNs)
    2019-01-01 Jadhav, S.A., Brunella, V., Sapino, S., Caprarelli B., Riedo, C., Chirio, D., Gallarate, M. https://iris.unito.it/handle/2318/1692215

    Thermosensitive nanocomposite hydrogels for intravitreal delivery of cefuroxime
    2019-01-01 Simona Sapino; Elena Peira; Daniela Chirio; Giulia Chindamo; Stefano Guglielmo; Simonetta Oliaro-Bosso; Raffaella Barbero; Cristina Vercelli; Giovanni Re; Valentina Brunella; Chiara Riedo; Antonio Maria Fea; Marina Gallarate https://iris.unito.it/handle/2318/1715088

    Development of Solid Lipid Nanoparticles by Cold Dilution of Microemulsions: Curcumin Loading, Preliminary In Vitro Studies, and Biodistribution
    2019-01-01 Chirio, Daniela; Peira, Elena; Dianzani, Chiara; Muntoni, Elisabetta; Gigliotti, Casimiro Luca; Ferrara, Benedetta; Sapino, Simona; Chindamo, Giulia; Gallarate, Marina https://iris.unito.it/handle/2318/1704549

    Sistemi nanocompositi termosensibili per la somministrazione intravitreale di cefuroxima
    2018-01-01 BRUNO CAPRARELLI, SIMONA SAPINO, ELENA PEIRA, DANIELA CHIRIO, SUSHIL A JADHAV, SIMONETTA OLIARO BOSSO, STEFANO GUGLIELMO, RAFFAELLA BARBERO, ANTONIO MARIA FEA, CLAUDIA FRUTTERO, FRANCO DOSIO, MARINA GALLARATE https://iris.unito.it/handle/2318/1685938

    Stearoyl-Chitosan Coated Nanoparticles Obtained by Microemulsion Cold Dilution Technique
    2018-01-01 Chirio, Daniela; Peira, Elena; Sapino, Simona; Dianzani, Chiara; Barge, Alessandro; Muntoni, Elisabetta; Morel, Silvia; Gallarate, Marina https://iris.unito.it/handle/2318/1685845

    Lipophilic prodrug of floxuridine loaded into solid lipid nanoparticles: In vitro cytotoxicity studies on different human cancer cell lines
    2018-01-01 Chirio, Daniela; Peira, Elena; Battaglia, Luigi; Ferrara, Benedetta; Barge, Alessandro; Sapino, Simona; Giordano, Susanna; Dianzani, Chiara; Gallarate, Marina https://iris.unito.it/handle/2318/1655802

    Solid lipid nanoparticles by coacervation loaded with a methotrexate prodrug: preliminary study for glioma treatment
    2017-01-01 Battaglia, L; Muntoni, E; Chirio, D; Peira, E; Annovazzi, L; Schiffer, D; Mellai, M; Riganti, C; Salaroglio, Ic; Lanotte, M; Panciani, P; Capucchio, Mt; Valazza, A; Biasibetti, E; Gallarate, M https://iris.unito.it/handle/2318/1627489

    Comparison of Allogeneic and Syngeneic Rat Glioma Models by Using MRI and Histopathologic Evaluation
    2017-01-01 Biasibetti, Elena; Valazza, Alberto; Capucchio, Maria T; Annovazzi, Laura; Battaglia, Luigi; Chirio, Daniela; Gallarate, Marina; Mellai, Marta; Muntoni, Elisabetta; Peira, Elena; Riganti, Chiara; Schiffer, Davide; Panciani, Pierpaolo; Lanotte, Michele https://iris.unito.it/handle/2318/1632007

    Solid Lipid Nanoparticles Loaded with Antitumor Lipophilic Prodrugs Aimed to Glioblastoma Treatment:
    2017-01-01 Annovazzi, Laura; Schiffer, Davide; Mellai, Marta; Gallarate, Marina; Battaglia, Luigi; Chirio, Daniela; Peira, Elena; Muntoni, Elisabetta; Chegaev, Konstantin; Barge, Alessandro; Lanotte, Michele; Panciani, Pierpaolo; Capucchio, Maria Teresa; Valazza, Alberto; Biasibetti, Elena; Riganti, Chiara https://iris.unito.it/handle/2318/1627515

    Recent studies on the delivery of hydrophilic drugs in nanoparticulate systems.
    2016-01-01 Arpicco, Silvia; Battaglia, Luigi; Brusa, Paola; Cavalli, Roberta; Chirio, Daniela; Dosio, Franco; Gallarate, Marina; Milla, Paola; Peira, Elena; Rocco, Flavio; Sapino, Simona; Stella, Barbara; Ugazio, Elena; Ceruti, Maurizio https://iris.unito.it/handle/2318/1525357

    Solid lipid nanoparticles carrying lipophilic derivatives of doxorubicin: preparation, characterization, and in vitro cytotoxicity studies
    2016-01-01 Peira, Elena; Chirio, Daniela; Battaglia, Luigi; Barge, Alessandro; Chegaev, Konstantin; Gigliotti, Casimiro Luca; Ferrara, Benedetta; Dianzani, Chiara; Gallarate, Marina https://iris.unito.it/handle/2318/1610005

    Experimental glioblastoma in Fisher rat model: treatment with a biocompatible system as carrier of methotrexate drug.
    2015-01-01 Biasibetti E; Valazza A; Battaglia L; Gallarate M; Peira E; Chirio D; Muntoni E; Panciani PP; Riganti C; Annovazzi L; Caldera V; Schiffer D; Lanotte M; Capucchio M.T. https://iris.unito.it/handle/2318/156754

    Bevacizumab loaded solid lipid nanoparticles prepared by the coacervation technique: preliminary in vitro studies
    2015-01-01 Battaglia, Luigi; Gallarate, Marina; Peira, Elena; Chirio, Daniela; Solazzi, Ilaria; Giordano, Susanna Marzia Adele; Gigliotti, Casimiro Luca; Riganti, Chiara; Dianzani, Chiara https://iris.unito.it/handle/2318/1520408

    The DNA damage/repair cascade in glioblastoma cell lines after chemotherapeutic agent treatment.
    2015-01-01 Annovazzi, Laura; Caldera, Valentina; Mellai, Marta; Riganti, Chiara; Battaglia, Luigi; Chirio, Daniela; Melcarne, Antonio; Schiffer, Davide https://iris.unito.it/handle/2318/1520405

    Solid lipid nanoparticles as antineoplastic drugs vehicles in glioblastoma multiforme: in vitro and in vivo pathological effects.
    2014-01-01 Biasibetti E.; Battaglia L.; Gallarate M.; Peira E.; Chirio D.; Muntoni E.; Valazza A.; Lanotte M.; Panciani P.P.; Riganti C.; Annovazzi L.; Caldera V.; Schiffer D.; Capucchio M.T. https://iris.unito.it/handle/2318/141589

    Nanoparticelle lipidiche solide per veicolare farmaci antitumorali oltre la barriera emato-encefalica, in particolare per il trattamento dei tumori cerebrali
    2014-01-01 L. Battaglia; M. Gallarate; E. Peira; D. Chirio; E. Muntoni; L. Gastaldi; E. Biasibetti; MT. Capucchio; A. Valazza; P. Panciani; M. Lanotte; D. Schiffer; L. Annovazzi; V. Caldera; M. Mellai; C. Riganti https://iris.unito.it/handle/2318/150727

    Techniques for the Preparation of Solid Lipid Nano and MicroparticlesApplication of Nanotechnology in Drug Delivery
    2014-01-01 L. Battaglia; M. Gallarate; P.P. Panciani; E. Ugazio; S. Sapino; E. Peira; D. Chirio https://iris.unito.it/handle/2318/155384

    Methotrexate loaded SLN obtained by coacervation for potential glioblastoma treatment
    2014-01-01 L. Battaglia; M. Gallarate; E. Peira; D. Chirio; L. Gastaldi; E. Muntoni; E. Biasibetti; M.T. Capucchio; A. Valazza; P. Panciani; M. Lanotte; D. Schiffer; L. Annovazzi; V. Caldera; C. Riganti https://iris.unito.it/handle/2318/155385

    Solid lipid nanoparticles as vehicles of drugs to the brain: Current state of the art
    2014-01-01 L. Gastaldi; L. Battaglia; E. Peira; D. Chirio; E. Muntoni; I. Solazzi; M. Gallarate; F. Dosio https://iris.unito.it/handle/2318/155381

    Positive-charged solid lipid nanoparticles as paclitaxel drug delivery system in glioblastoma treatment
    2014-01-01 Daniela Chirio;Marina Gallarate;Elena Peira;Luigi Battaglia;Elisabetta Muntoni;Chiara Riganti;Elena Biasibetti;Maria Teresa Capucchio;Alberto Valazza;Pierpaolo Panciani;Michele Lanotte;Laura Annovazzi;Valentina Caldera;Marta Mellai;Gaetano Filice;Silvia Corona;Davide Schiffer https://iris.unito.it/handle/2318/150103

    SLN prodotte attraverso la tecnica della coacervazione come veicoli di macromolecole idrofile
    2014-01-01 I. Solazzi; L. Battaglia; M. Gallarate; E. Peira; D. Chirio; S. Giordano; V. Dolo; C. Dianzani https://iris.unito.it/handle/2318/155386

    Solid Lipid Nanoparticles for Potential Doxorubicin
    2014-01-01 L. Battaglia; M. Gallarate; E. Peira; D. Chirio; E. Muntoni; E. Biasibetti; https://iris.unito.it/handle/2318/145777

    The influence of surface charge and photo-reactivity on skin-permeation enhancer property of nano-TiO2 in ex vivo pig skin model under indoor light
    2014-01-01 Peira, Elena; Turci, Francesco; Corazzari, Ingrid; Chirio, Daniela; Battaglia, Luigi Sebastiano; Fubini, Bice; Gallarate, Marina https://iris.unito.it/handle/2318/155488

    Solid Lipid Nanoparticles Loaded with Fluorescent-labelled Cyclosporine A: Anti-inflammatory Activity in Vitro
    2014-01-01 Gallarate, M.; Serpe, L.; Foglietta, F.; Giordano, S.; Peira, E.; Chirio, D.; Battaglia, L. https://iris.unito.it/handle/2318/155522

    Solid lipid nanoparticles as antineoplastic drug vehicles in glioblastoma multiforme. invitro and in vivo pathological effects
    2013-01-01 E.Biasibetti; L.Battaglia; M.Gallarate; E.Peira; D.Chirio; E.Muntoni*; A.Valazza; M.Lanotte; PP.Panciani; C.Riganti; L.Annovazzi; V.Caldera; D.Schiffer; M.T.Capucchio https://iris.unito.it/handle/2318/140298

    SLN obtained by coacervation for potential anti-tumour drug delivery to the brain.
    2013-01-01 L. Battaglia; M.Gallarate; E. Peira; D. Chirio; E. Muntoni; F. Dosio; E. Biasibetti; M.T.Capucchio; A.Valazza; P. Panciani; M.Lanotte; D.Schiffer; L. Annovazzi;V.Caldera; C.Riganti. https://iris.unito.it/handle/2318/141596

    MCM-41 as a useful vector for rutin topical formulation: Synthesis, characterization and testing
    2013-01-01 Berlier G; Gastaldi L; Sapino S; Miletto I; Bottinelli E; Chirio D; Ugazio E https://iris.unito.it/handle/2318/146325

    Development of O/W nanoemulsions for ophthalmic administration of timolol
    2013-01-01 Marina, Gallarate; Daniela, Chirio; Rosanna, Bussano; Elena, Peira; Luigi, Sebastiano Battaglia; Francesca, Baratta; Michele, Trotta https://iris.unito.it/handle/2318/125674

    Sistemi microemulsivi per la somministrazione oftalmica di bevacizumab
    2012-01-01 Elena Peira; Luigi Battaglia; Daniela Chirio; Marina Gallarate; Michele Trotta https://iris.unito.it/handle/2318/140337

    SLN per la veicolazione di un analogo fluorescente della Ciclosporina A
    2012-01-01 Luigi Battaglia; Loredana Serpe; Gian Paolo Zara; Daniela Chirio; Marina Gallarate; Elena Peira; Michele Trotta https://iris.unito.it/handle/2318/139304

    Formulation of curcumin-loaded solid lipid nanoparticlesproduced by fatty acids coacervation technique
    2011-01-01 DANIELA CHIRIO; MARINA GALLARATE; ELENA PEIRA; LUIGI BATTAGLIA ; LOREDANA SERPE; MICHELE TROTTA https://iris.unito.it/handle/2318/95359

    Thermosensitive gels for the topical administration of diltiazem
    2011-01-01 Daniela Chirio; Michele Trotta; Marina Gallarate; Elena Peira; M.Eugenia Carlotti https://iris.unito.it/handle/2318/86155

    Preparation and characterization of insulin-loaded lipid-based microspheres generated by electrospray
    2011-01-01 Bussano R.; Chirio D.; Costa L.; Turci F.; Trotta M. https://iris.unito.it/handle/2318/139496

    Thermogelling microemulsions for topical delivery of griseofulvin
    2011-01-01 E. Peira; M. Gallarate; R. Spagnolo; D. Chirio; M. Trotta https://iris.unito.it/handle/2318/89626

    Cisplatin-loaded SLN produced by coacervation technique
    2010-01-01 M. Gallarate; M. Trotta; L. Battaglia; D. Chirio https://iris.unito.it/handle/2318/78575

    Synthesis, characterization and potential application of monoacyl-cyclodextrins
    2010-01-01 Martina K; Puntambekar DS; Barge A; Gallarate M; Chirio D; Cravotto G https://iris.unito.it/handle/2318/74790

    Preparation of solid lipid nanoparticles from W/O/W emulsions: Preliminary studies on insulin encapsulation
    2009-01-01 Marina GALLARATE; Michele TROTTA; Luigi Sebastiano BATTAGLIA; Daniela CHIRIO https://iris.unito.it/handle/2318/61993

    Influence of alpha- and gamma- cyclodextrin lipophilic derivativeson curcumin-loaded SLN
    2009-01-01 Chirio D.; Gallarate M.; Trotta M.; Carlotti M.E.; Calcio Gaudino E.; Cravotto G. https://iris.unito.it/handle/2318/62900

    Photostability and antioxidant properties of quercetin free and complexed with methyl- β-cyclodextrin
    2009-01-01 M.E. Carlotti; S. Sapino; E. Ugazio; E. Peira; D. Chirio https://iris.unito.it/handle/2318/139403

    Formulation studies of microemulsions for topical applications of acyclovir
    2009-01-01 E. Peira; D. Chirio; M.E. Carlotti; R. Spagnolo; M. Trotta https://iris.unito.it/handle/2318/73464

    Effects of γ-cyclodextrin dodecyl carbonate on curcumin-loaded SLN
    2008-01-01 CHIRIO D.; TROTTA M.; GALLARATE M.; CARLOTTI M.E.; SPAGNOLO R. https://iris.unito.it/handle/2318/112756

    Self-emulsifying drug delivery systems containing pindolol
    2008-01-01 E. Peira; D. Chirio; M.E. Carlotti; M. Trotta https://iris.unito.it/handle/2318/140204

    Influence of hydroxypropyl-beta-cyclodextrin on the photostability and antiradical activity of Trolox
    2008-01-01 Carlotti, M.E.; Sapino, S.; Marino, S.; Ugazio, E.; Trotta, F.; Vione, D.; Chirio, D.; Cavalli, R. https://iris.unito.it/handle/2318/52570

    Assorbimento percutaneo di L-carnitina. Studi preclinici in vitro
    2007-01-01 CARLOTTI M; BATTAGLIA L; SAPINO S; PEIRA E; CHIRIO D; UGAZIO E; VIGLIERCHIO D https://iris.unito.it/handle/2318/27482

    Trilaurine and dodecyl carbonate of cyclodextrin nanoparticles for curcumine delivery
    2007-01-01 D. Chirio; M.E. Carlotti; E. Peira; M. Trotta https://iris.unito.it/handle/2318/56823

    Deformable liposomes containing alkylcarbonates of γ-cyclodextrins for dermal applications
    2007-01-01 D. CHIRIO; R. CAVALLI; F. TROTTA; M.E. CARLOTTI; M. TROTTA https://iris.unito.it/handle/2318/40113

    Deformable liposomes containing alkylcarbonates of gamma-cyclodextrin for dermal applications
    2007-01-01 D Chirio; R Cavalli; F Trotta; ME Carlotti; M Trotta https://iris.unito.it/handle/2318/98319

    Elastic positively-charged liposomes for topical administration of acyclovir
    2007-01-01 PEIRA E; TROTTA M; CARLOTTI M.E; GALLARATE M; CHIRIO D https://iris.unito.it/handle/2318/39379

    Deformable liposomes as topical formulations containing α-tocopherol
    2006-01-01 M. GALLARATE; D. CHIRIO; M. TROTTA; M.E. CARLOTTI https://iris.unito.it/handle/2318/37624

    Elastic positively charged liposomes for topical administration of acyclovir
    2006-01-01 Elena Peira; Elena Ugazio; Daniela Chirio; Michele Trotta https://iris.unito.it/handle/2318/140339

    Hydrophilic microspheres from water-in-oil emulsions by the water diffusion technique
    2004-01-01 TROTTA M; CHIRIO D; CAVALLI R; PEIRA E https://iris.unito.it/handle/2318/99721

    Courses

    Research topics

    -Collaborazione con School of Nanoscience and Technology, Shivaji University Kolhapur

    -Collaborazione con Microsurgery Department di Caceres, Spagna

     

    -Collaborazione con il Centro di Neuro-Bio-Oncologia Fondazione Policlinico di Monza

    -Collaborazione con l’Interdisciplinary Research Center of Autoimmune Diseases, Department of Health Sciences, ‘A. Avogadro’ University of Eastern Piedmont, Novara.

    -Collaborazione con dell’Istituto Zooprofilattico Sperimentale del Piemonte-Liguria-Valle d’Aosta

    - Collaborazione con il Dipartimento di Oncologia e di Scienze veterinarie, Università degli studi di Torino

     

    1. Chindamo G.; Sapino S.; Peira E.; Chirio D.; Gallarate M. (2021). Recent advances in nanosystems and strategies for vaginal delivery of antimicrobials, NANOMATERIALS, 11, 1-29, doi: 10.3390/nano11020311.
    2. Chirio D.; Peira E.; Sapino S.; Chindamo G.; Oliaro-bosso S.; Adinolfi S.; Dianzani C.; Baratta F.; Gallarate M. (2021). A new bevacizumab carrier for intravitreal administration: Focus on stability. PHARMACEUTICS, 13, 560-577, doi: 10.3390/pharmaceutics13040560.
    3. Gallarate M.; Chirio D.; Chindamo G.; Peira E.; Sapino S. (2021). Osteomyelitis: Focus on Conventional Treatments and Innovative Drug Delivery Systems. CURRENT DRUG DELIVERY, 18, 532-545, doi: 10.2174/1567201817666200915093224.
    4. Argenziano M.; Arpicco S.; Brusa P.; Cavalli R.; Chirio D.; Dosio F.; Gallarate M.; Peira E. et al. (2021). Developing actively targeted nanoparticles to fight cancer: Focus on italian research. PHARMACEUTICS, 13, 1538-1567, doi: 3390/pharmaceutics13101538.
    5. Sapino S.; Chindamo G.; Chirio D.; Manzoli M.; Peira E.; Riganti C.; Gallarate M. (2021). Calcium Phosphate-Coated Lipid Nanoparticles as a Potential Tool in Bone Diseases Therapy. NANOMATERIALS, 11, 2983-2999. doi: 10.3390/nano11112983.
    6. Peira E.; Chindamo G.; Chirio D.; Sapino S.; Oliaro-bosso S.; Rebba E.; Ivanchenko P. et al. (2021). Assessment of in‐situ gelling microemulsion systems upon temperature and dilution. PHARMACEUTICS, 13, 1-20. doi: 10.3390/pharmaceutics13020258.
    7. Chindamo G.; Sapino S.; Peira E.; Chirio D.; Gonzalez M.C.; Gallarate M. (2020). Bone diseases: Current approach and future perspectives in drug delivery systems for bone targeted therapeutics. NANOMATERIALS, 10, 875. doi:10.3390/nano10050875.
    8. Abd-Ellatef G.-E.F.; Gazzano E.; Chirio, D.; Abdel-Hamid, A.-H.Z.; et al. (2020). Curcumin-loaded solid lipid nanoparticles bypass p-glycoprotein mediated doxorubicin resistance in triple negative breast cancer cells. PHARMACEUTICS, 12, 96. doi:10.3390/pharmaceutics12020096.
    9. Chirio D.; Peira E.; Dianzani C.; Muntoni E.; Gigliotti C.L.; Ferrara B.; Sapino S.; Chindamo G.; Gallarate M. (2019). Development of solid lipid nanoparticles by cold dilution of microemulsions: curcumin loading, preliminary in vitro studies, and biodistribution. NANOMATERIALS, 9, 230-247, doi: 10.3390/nano9020230.
    10. Sapino S.; Chirio D.; Peira E.; Abellán Rubio E.; Brunella V.; Jadhav S.A.; Chindamo G.; Gallarate M. (2019). Ocular Drug Delivery: A Special Focus on the Thermosensitive Approach. NANOMATERIALS, vol. 9, 884-902, doi: 10.3390/nano9060884.
    11. Sapino S.; Peira E.; Chirio D.; et al. Thermosensitive nanocomposite hydrogels for intravitreal delivery of cefuroxime (2019). NANOMATERIALS, 9, 1461. doi:10.3390/nano9101461.
    12. Jadhav S.A.; Brunella V.; Sapino S.; Caprarelli B.; Riedo C.; Chirio D.; Gallarate M. (2019). Poly (N-isopropylacrylamide) based hydrogels as novel precipitation and stabilization media for solid lipid nanoparticles. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 541, 454-460, doi: 10.1016/j.jcis.2019.01.107.
    13. Chirio D.; Peira E.; Sapino S.; Dianzani C.; Barge A.; Muntoni E.; Morel S.; Gallarate M. (2018). Stearoyl-Chitosan Coated Nanoparticles Obtained by Microemulsion Cold Dilution Technique. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 19, 3833-3849, doi: 10.3390/ijms19123833.
    14. Chirio D.; Peira E.; Battaglia L.; Ferrara B.; Barge A.; Sapino S.; Giordano S.; Dianzani C.; Gallarate M. (2018). Lipophilic prodrug of floxuridine loaded into solid lipid nanoparticles: In vitro cytotoxicity studies on different human cancer cell lines. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, 18, 556-563, doi:https://doi.org/10.1166/jnn.2018.13964.
    15. Annovazzi L.; Schiffer D.; Mellai M.; Gallarate M.; Battaglia L.; Chirio D.; Peira E.; Muntoni E.; Chegaev K.; Barge A.; Lanotte M. et al. (2017). Solid lipid nanoparticles loaded with antitumor lipophilic prodrugs aimed to glioblastoma treatment: Preliminary studies on cultured cells. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, 17, 3606-3614, doi: 10.1166/jnn.2017.13001.
    16. Battaglia L.; Muntoni E.; Chirio D.; Peira E.; Annovazzi L.; Schiffer D.; Mellai M.; Riganti C.; Salaroglio I.; Lanotte M.; Panciani P.; Capucchio M.T.; Valazza A.; Biasibetti E.; Gallarate M. (2017). Solid lipid nanoparticles by coacervation loaded with a methotrexate prodrug: preliminary study for glioma treatment. NANOMEDICINE, 12, 639-656, doi: 10.2217/nnm-2016-0380.
    17. Biasibetti E.; Valazza A.; Capucchio M.T.; Annovazzi L.; Battaglia L.; Chirio D.; Gallarate M.; Mellai M.; Muntoni E.; Peira E.; Riganti C.; Schiffer D.; Panciani P.; Lanotte M. (2017). Comparison of allogeneic and syngeneic rat glioma models by using mri and histopathologic evaluation. COMPARATIVE MEDICINE, 67, 147-156.
    18. Arpicco S.M.; Battaglia L.S.; Brusa P.; Cavalli R.; Chirio D.; Dosio F.; Gallarate M.; Milla P.; Peira E.; Rocco F.; Sapino S.; Stella B.; Ugazio E.; Ceruti M. (2016). Recent studies on the delivery of hydrophilic drugs in nanoparticulate systems. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 32, 298-312, doi: 10.1016/j.jddst.2015.09.004.
    19. Peira E.; Chirio D.; Battaglia L.S.; Barge A.; Chegaev K.; Gigliotti C.L.; Ferrara B.; Dianzani C.; Gallarate M. (2016). Solid lipid nanoparticles carrying lipophilic derivatives of doxorubicin: preparation, characterization, and in vitro cytotoxicity studies. JOURNAL OF MICROENCAPSULATION, 33, 381-390, doi: 1080/02652048.2016.1202342.
    20. Battaglia L.; Gallarate M.; Peira E.; Chirio D.; Solazzi I.; Giordano S.M.A.; Gigliotti C.L.; Riganti C.; Dianzani C. (2015). Bevacizumab loaded solid lipid nanoparticles prepared by the coacervation technique: preliminary in vitro studies. NANOTECHNOLOGY, 26, 255102-255112, doi:10.1088/0957-4484/26/25/255102.
    21. Annovazzi L.; Caldera V.; Mellai M.; Riganti C.; Battaglia L.; Chirio D.; Melcarne A.; Schiffer D. (2015). The DNA damage/repair cascade in glioblastoma cell lines after chemotherapeutic agent treatment. INTERNATIONAL JOURNAL OF ONCOLOGY, 46, 2299-2308, doi: 10.3892/ijo.2015.2963.
    22. Gallarate M.; Serpe L.; Foglietta F.; Giordano S.; Peira E.; Chirio D.; Battaglia L. (2014). Solid Lipid Nanoparticles Loaded with Fluorescent-labelled Cyclosporine A: Anti-inflammatory Activity in Vitro. PROTEIN & PEPTIDE LETTERS, 21, 1157-1162, doi: 10.2174/0929866521666140806164410.
    23. Gastaldi L.; Battaglia L.; Peira E.; Chirio D.; Muntoni E.; Solazzi I.; Gallarate M.; Dosio F. (2014). Solid lipid nanoparticles as vehicles of drugs to the brain: Current state of the art. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 87, 433-444. doi: 10.1016/j.ejpb.2014.05.004.
    24. Peira E.; Turci F.; Corazzari I.; Chirio D.; Battaglia L.S.; Fubini B.; Gallarate M. (2014). The influence of surface charge and photo-reactivity on skin-permeation enhancer property of nano-TiO2 in ex vivo pig skin model under indoor light. INTERNATIONAL JOURNAL OF PHARMACEUTICS, vol. 467, p. 90-99, ISSN: 0378-5173, doi: 10.1016/j.ijpharm.2014.03.052
    25. Chirio D.; Gallarate M.; Peira, E.; Corona, S., et al. (2014). Positive-charged solid lipid nanoparticles as paclitaxel drug delivery system in glioblastoma treatment. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 88, 746–758. doi: 10.1016/j.ejpb.2014.10.017.
    26. Battaglia L.; Gallarate M.; Peira E.; Chirio D.; Muntoni E.; Biasibetti E.; Capucchio M.T.; Valazza A.; Panciani P.P.; Lanotte M.; Schiffer D. et al. (2014). Solid lipid nanoparticles for potential doxorubicin delivery in glioblastoma treatment: preliminary in vitro studies. JOURNAL OF PHARMACEUTICAL SCIENCES, 103, 2157-2165, doi: 10.1002/jps.24002.
    27. Berlier G.; Gastaldi L.; Sapino S.; Miletto I.; Bottinelli E.; Chirio D.; Ugazio E. (2013). MCM-41 as a useful vector for rutin topical formulation: Synthesis, characterization and testing. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 457, 177-186, doi: 10.1016/j.ijpharm.2013.09.018.
    28. Gallarate M.; Chirio D.; Bussano R.; Peira E.; Battaglia L.S.; Baratta F.; Trotta M. (2013). Development of O/W nanoemulsions for ophthalmic administration of timolol. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 440, 126-134, doi: 10.1016/j.ijpharm.2012.10.015.
    29. Chirio D.; Trotta M.; Gallarate M.; Peira E.; Carlotti M.E. (2011). Thermosensitive gels for the topical administration of diltiazem. JOURNAL OF DISPERSION SCIENCE AND TECHNOLOGY, 32, 320-325. doi: 10.1080/01932691003659684.
    30. Chirio D.; Gallarate M.; Peira E.; Battaglia L.; Serpe L.; Trotta M. (2011). Formulation of curcumin-loaded solid lipid nanoparticles produced by fatty acids coacervation technique. JOURNAL OF MICROENCAPSULATION, 28, 537-548. doi: 10.3109/02652048.2011.590615.
    31. Bussano R.; Chirio D.; Costa L.; Turci F.; Trotta M. (2011). Preparation and characterization of insulin-loaded lipid-based microspheres generated by electrospray. JOURNAL OF DISPERSION SCIENCE AND TECHNOLOGY, 32, 1524-1530, doi: 10.1080/01932691.2010.505876.
    32. Peira E.; Gallarate M.; Spagnolo R.; Chirio D.; Trotta M. (2011). Thermogelling microemulsions for topical delivery of griseofulvin. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 21, 497-501, doi: 10.1016/S1773-2247(11)50080-2.
    33. Martina K.; Puntambekar D.S.; Barge A.; Gallarate M.; Chirio D.; Cravotto G. (2010). Synthesis, characterization and potential application of monoacyl-cyclodextrins. CARBOHYDRATE RESEARCH, 345, 191-198, doi: 10.1016/j.carres.2009.11.009.
    34. Gallarate M.; Trotta M.; Battaglia L.; Chirio D. (2010). Cisplatin-loaded SLN produced by coacervation technique. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 20, 343-347.
    35. Gallarate M.; Trotta M.; Battaglia L.S.; Chirio D. (2009). Preparation of solid lipid nanoparticles from W/O/W emulsions: Preliminary studies on insulin encapsulation. JOURNAL OF MICROENCAPSULATION, 26, 394-402, doi:10.1080/02652040802390156.
    36. Peira E.; Chirio D.; Carlotti M.E.; Spagnolo R.; Trotta M. (2009). Formulation studies of microemulsions for topical applications of acyclovir. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 19, 191-196.
    37. Chirio D.; Gallarate M.; Trotta M.; Carlotti M.E.; Calcio Gaudino E.; Cravotto G. (2009). Influence of alpha- and gamma- cyclodextrin lipophilic derivatives on curcumin-loaded SLN. JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY, 65, 391-402, doi: 10.1007/s10847-009-9597-7.
    38. Carlotti, M.E.; Sapino, S.; Marino, S.; Ugazio, E.; Trotta, F.; Vione, D.; Chirio, D.; Cavalli, R. (2008). Influence of hydroxypropyl-beta-cyclodextrin on the photostability and antiradical activity of Trolox. JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY, 61, 279-287.
    39. Carlotti M.E.; Battaglia L.; Sapino S.; Peira E.; Chirio D.; Ugazio E.; Viglierchio D. (2007). COSMETIC TECHNOLOGY 10, 11-16.
    40. Chirio D.; Cavalli R.; Trotta F.; Carlotti M.E.; Trotta M. (2007). Deformable liposomes containing alkylcarbonates of gamma-cyclodextrin for dermal applications. JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY, 57, 645-649. doi: 10.1007/s10847-006-9271-2
    41. Peira E.; Trotta M.; Carlotti M.E.; Gallarate M.; Chirio D. (2007). Elastic positively-charged liposomes for topical administration of acyclovir. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY 17, 321-324.
    42. Gallarate M.; Chirio D.; Trotta M.; M.E. Carlotti (2006). Deformable liposomes as topical formulations containing α-tocopherol. JOURNAL OF DISPERSION SCIENCE AND TECHNOLOGY 27, 703-713.
    43. Trotta M.; Chirio D.; Cavalli R.; Peira E. (2004). Hydrophilic microspheres from water-in-oil emulsions by the water diffusion technique. PHARMACEUTICAL RESEARCH, 21, 1445-1449.
    44. Trotta, M.; Cavalli, R.; Chirio, D. (2003). Griseofulvin nanosuspensions from triacetin-in-water emulsions. S.T.P. Pharma Sciences 13, 423–426.

     

     - “Development of solid lipid nanoparticles (SLN) as vehicles of antineoplastic drugs to improve the pharmacological glioblastoma therapy” FINANZIATO dalla COMPAGNIA DI SAN PAOLO nel 2011. Durata di 24 mesi. Il progetto di ricerca ha previsto la partecipazione di ricercatori appartenenti ad Unito (Gallarate M, Chirio D, Peira E, Battaglia L. Valazza A., Capucchio M.T, Biasibetti E) e al Centro di Neuro-Bio-Oncologia Policlinico di Monza (Schiffer D, Annovazzi L, Mellai, Caldera V).

    - Development of oxidic and polymeric materials for stimuli responsive applications (OXYPOLISTI) FINANZIATO dalla COMPAGNIA DI SAN PAOLO nel 2011. Durata di 36 mesi. Il progetto di ricerca ha previsto la collaborazione di ricercatori di Unito (coordinatore prof.ssa Gloria Berlier) e del Dott. M. Lazzari, University of Santiago de Compostela, Spain.

    - “Idrogeli nanocompositi termosensibili per il rilascio intravitreale di cefuroxima” FINANZIATO da Fondazione CRT nel 2017 che ha previsto la collaborazione di ricercatori appartenenti ad Unito (Sapino S, Chirio D, Peira E, Gallarate M), dell’Azienda Ospedaliera Ordine Mauriziano di Torino (Fruttero C), dell’ospedale Oftalmico di Torino (Fea A), dell’Istituto Zooprofilattico Sperimentale del Piemonte-Liguria-Valle d’Aosta (Barbero R) e del Microsurgery Department (Jesús Usón Minimally Invasive Surgery Centre) di Caceres, Spagna (Rubio E.A).

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