Department of Drug Science and Technology

Research products

Selected research products

Marengo A, Maciel LS, Cagliero C, Rubiolo P, Herodes K. (2023) Free Amino Acids and Biogenic Amines Profiling and Variation in Wild and Sub-Endemic Cardueae Species from Sardinia and Corse. Plants (Basel, Switzerland) 12(2) [DOI  PMID]

Strocchi G, Rubiolo P, Cordero C, Bicchi C, Liberto E. (2022) Acrylamide in coffee: What is known and what still needs to be explored. A review. Food chemistry 393 133406 [DOI  PMID]

Mastellone G, Marengo A, Sgorbini B, Scaglia F, Capetti F, Gai F, Peiretti PG, Rubiolo P, Cagliero C. (2022) Characterization and Biological Activity of Fiber-Type Cannabis sativa L. Aerial Parts at Different Growth Stages. Plants (Basel, Switzerland) 11(3) [DOI  PMID]

Cagliero C, Bizzo H, Rubiolo P, Marengo A, Galli S, Anderson JL, Sgorbini B, Bicchi C. (2022) Immobilization of phosphonium-based ionic liquid stationary phases extends their operative range to routine applications in the flavor, fragrance and natural product fields. Journal of chromatography. A 1664 462796 [DOI  PMID]

Cagliero C, Bicchi C, Marengo A, Rubiolo P, Sgorbini B. (2022) Gas chromatography of essential oil: State-of-the-art, recent advances, and perspectives. Journal of separation science 45(1) 94-112 [DOI  PMID]

Sanna C, Marengo A, Acquadro S, Caredda A, Lai R, Corona A, Tramontano E, Rubiolo P, Esposito F. (2021) In Vitro Anti-HIV-1 Reverse Transcriptase and Integrase Properties of Punica granatum L. Leaves, Bark, and Peel Extracts and Their Main Compounds. Plants (Basel, Switzerland) 10(10) [DOI  PMID]

Capetti F, Marengo A, Cagliero C, Liberto E, Bicchi C, Rubiolo P, Sgorbini B. (2021) Adulteration of Essential Oils: A Multitask Issue for Quality Control. Three Case Studies: Lavandula angustifolia Mill., Citrus limon (L.) Osbeck and Melaleuca alternifolia (Maiden & Betche) Cheel. Molecules (Basel, Switzerland) 26(18) [DOI  PMID]

Maciel LS, Marengo A, Rubiolo P, Leito I, Herodes K. (2021) Derivatization-targeted analysis of amino compounds in plant extracts in neutral loss acquisition mode by liquid chromatography-tandem mass spectrometry. Journal of chromatography. A 1656 462555 [DOI  PMID]

Capetti F, Tacchini M, Marengo A, Cagliero C, Bicchi C, Rubiolo P, Sgorbini B. (2021) Citral-Containing Essential Oils as Potential Tyrosinase Inhibitors: A Bio-Guided Fractionation Approach. Plants (Basel, Switzerland) 10(5) [DOI  PMID]

Gabetti E, Sgorbini B, Stilo F, Bicchi C, Rubiolo P, Chialva F, Reichenbach SE, Bongiovanni V, Cordero C, Cavallero A. (2021) Chemical fingerprinting strategies based on comprehensive two-dimensional gas chromatography combined with gas chromatography-olfactometry to capture the unique signature of Piemonte peppermint essential oil (Mentha x piperita var Italo-Mitcham). Journal of chromatography. A 1645 462101 [DOI  PMID]

Cagliero C, Mastellone G, Marengo A, Bicchi C, Sgorbini B, Rubiolo P. (2021) Analytical strategies for in-vivo evaluation of plant volatile emissions - A review. Analytica chimica acta 1147 240-258 [DOI  PMID]

Capetti F, Cagliero C, Marengo A, Bicchi C, Rubiolo P, Sgorbini B. (2020) Bio-Guided Fractionation Driven by In Vitro alpha-Amylase Inhibition Assays of Essential Oils Bearing Specialized Metabolites with Potential Hypoglycemic Activity. Plants (Basel, Switzerland) 9(9) [DOI  PMID]

Acquadro S, Civra A, Cagliero C, Marengo A, Ritta M, Francese R, Sanna C, Bertea C, Sgorbini B, Lembo D, Donalisio M, Rubiolo P. (2020) Punica granatum Leaf Ethanolic Extract and Ellagic Acid as Inhibitors of Zika Virus Infection. Planta medica 86(18) 1363-1374 [DOI  PMID]

Aiello N, Marengo A, Scartezzini F, Fusani P, Sgorbini B, Rubiolo P, Cagliero C. (2020) Evaluation of the Farming Potential of Echinacea Angustifolia DC. Accessions Grown in Italy by Root-Marker Compound Content and Morphological Trait Analyses. Plants (Basel, Switzerland) 9(7) [DOI  PMID]

Mastellone G, Pacheco-Fernandez I, Rubiolo P, Pino V, Cagliero C. (2020) Sustainable Micro-Scale Extraction of Bioactive Phenolic Compounds from Vitis vinifera Leaves with Ionic Liquid-Based Surfactants. Molecules (Basel, Switzerland) 25(13) [DOI  PMID]

Moglia A, Florio FE, Iacopino S, Guerrieri A, Milani AM, Comino C, Barchi L, Marengo A, Cagliero C, Rubiolo P, Toppino L, Rotino GL, Lanteri S, Bassolino L. (2020) Identification of a new R3 MYB type repressor and functional characterization of the members of the MBW transcriptional complex involved in anthocyanin biosynthesis in eggplant (S. melongena L.). PloS one 15(5) e0232986 [DOI  PMID]

Capetti F, Sgorbini B, Cagliero C, Argenziano M, Cavalli R, Milano L, Bicchi C, Rubiolo P. (2020) Melaleuca alternifolia Essential Oil: Evaluation of Skin Permeation and Distribution from Topical Formulations with a Solvent-Free Analytical Method. Planta medica 86(6) 442-450 [DOI  PMID]

Cagliero C, Mazzucotelli M, Rubiolo P, Marengo A, Galli S, Anderson JL, Sgorbini B, Bicchi C. (2020) Can the selectivity of phosphonium based ionic liquids be exploited as stationary phase for routine gas chromatography? A case study: The use of trihexyl(tetradecyl) phosphonium chloride in the flavor, fragrance and natural product fields. Journal of chromatography. A 1619 460969 [DOI  PMID]

Capetti F, Rubiolo P, Bicchi C, Marengo A, Sgorbini B, Cagliero C. (2020) Exploiting the versatility of vacuum-assisted headspace solid-phase microextraction in combination with the selectivity of ionic liquid-based GC stationary phases to discriminate Boswellia spp. resins through their volatile and semivolatile fractions. Journal of separation science 43(9-10) 1879-1889 [DOI  PMID]

Acquadro S, Appleton S, Marengo A, Bicchi C, Sgorbini B, Mandrone M, Gai F, Peiretti PG, Cagliero C, Rubiolo P. (2020) Grapevine Green Pruning Residues as a Promising and Sustainable Source of Bioactive Phenolic Compounds. Molecules (Basel, Switzerland) 25(3) [DOI  PMID]

Ritta M, Marengo A, Civra A, Lembo D, Cagliero C, Kant K, Lal UR, Rubiolo P, Ghosh M, Donalisio M. (2020) Antiviral Activity of a Arisaema Tortuosum Leaf Extract and Some of its Constituents against Herpes Simplex Virus Type 2. Planta medica 86(4) 267-275 [DOI  PMID]

Negroni MS, Marengo A, Caruso D, Tayar A, Rubiolo P, Giavarini F, Persampieri S, Sangiovanni E, Davanzo F, Carugo S, Colombo ML, Dell'Agli M. (2019) A Case Report of Accidental Intoxication following Ingestion of Foxglove Confused with Borage: High Digoxinemia without Major Complications. Case reports in cardiology 2019 9707428 [DOI  PMID]

Perotti P, Cordero C, Bortolini C, Rubiolo P, Bicchi C, Liberto E. (2020) Cocoa smoky off-flavor: Chemical characterization and objective evaluation for quality control. Food chemistry 309 125561 [DOI  PMID]

Mazzucotelli M, Minteguiaga MA, Sgorbini B, Sidisky L, Marengo A, Rubiolo P, Bicchi C, Cagliero C. (2020) Ionic liquids as water-compatible GC stationary phases for the analysis of fragrances and essential oils: Quantitative GC-MS analysis of officially-regulated allergens in perfumes. Journal of chromatography. A 1610 460567 [DOI  PMID]

Marengo A, Emaus MN, Bertea CM, Bicchi C, Rubiolo P, Cagliero C, Anderson JL. (2019) Arabidopsis thaliana ITS sequence-specific DNA extraction by ion-tagged oligonucleotides coupled with a magnetic ionic liquid. Analytical and bioanalytical chemistry 411(25) 6583-6590 [DOI  PMID]

Marengo A, Cagliero C, Sgorbini B, Anderson JL, Emaus MN, Bicchi C, Bertea CM, Rubiolo P. (2019) Development of an innovative and sustainable one-step method for rapid plant DNA isolation for targeted PCR using magnetic ionic liquids. Plant methods 15 23 [DOI  PMID]

Marengo A, Maxia A, Sanna C, Mandrone M, Bertea CM, Bicchi C, Sgorbini B, Cagliero C, Rubiolo P. (2019) Intra-specific variation in the little-known Mediterranean plant Ptilostemon casabonae (L.) Greuter analysed through phytochemical and biomolecular markers. Phytochemistry 161 21-27 [DOI  PMID]

Sgorbini B, Cagliero C, Acquadro S, Marengo A, Cordero C, Liberto E, Bicchi C, Rubiolo P. (2019) Evaluation of volatile bioactive secondary metabolites transfer from medicinal and aromatic plants to herbal teas: Comparison of different methods for the determination of transfer rate and human intake. Journal of chromatography. A 1594 173-180 [DOI  PMID]

Sgorbini B, Cagliero C, Liberto E, Rubiolo P, Bicchi C, Cordero C. (2019) Strategies for Accurate Quantitation of Volatiles from Foods and Plant-Origin Materials: A Challenging Task. Journal of agricultural and food chemistry 67(6) 1619-1630 [DOI  PMID]

Mazzucotelli M, Bicchi C, Marengo A, Rubiolo P, Galli S, Anderson JL, Sgorbini B, Cagliero C. (2019) Ionic liquids as stationary phases for gas chromatography-Unusual selectivity of ionic liquids with a phosphonium cation and different anions in the flavor, fragrance and essential oil analyses. Journal of chromatography. A 1583 124-135 [DOI  PMID]

Bressanello D, Liberto E, Cordero C, Sgorbini B, Rubiolo P, Pellegrino G, Ruosi MR, Bicchi C. (2018) Chemometric Modeling of Coffee Sensory Notes through Their Chemical Signatures: Potential and Limits in Defining an Analytical Tool for Quality Control. Journal of agricultural and food chemistry 66(27) 7096-7109 [DOI  PMID]

Azzollini A, Boggia L, Boccard J, Sgorbini B, Lecoultre N, Allard PM, Rubiolo P, Rudaz S, Gindro K, Bicchi C, Wolfender JL. (2018) Dynamics of Metabolite Induction in Fungal Co-cultures by Metabolomics at Both Volatile and Non-volatile Levels. Frontiers in microbiology 9 72 [DOI  PMID]

Cagliero C, Bicchi C, Cordero C, Liberto E, Rubiolo P, Sgorbini B. (2018) Ionic liquids as water-compatible GC stationary phases for the analysis of fragrances and essential oils. Analytical and bioanalytical chemistry 410(19) 4657-4668 [DOI  PMID]

Courses

• Advances in Phytochemistry
  Dottorato in Scienze Farmaceutiche e Biomolecolari
• Botanica farmaceutica e metabolismo secondario vegetale (STF0048)
  Corsi di studio in
  Farmacia - Chimica e tecnologia farmaceutiche
• Farmacognosia con Saggi e Dosaggi (Tecniche Erboristiche) (STF0297A)
  Corso di Laurea in Tecniche Erboristiche

Research groups

• Pharmaceutical Biology and Food Chemistry
• Pharmaceutical Biology (PHYTOCHEM)

Research projects

• Essenza del Territorio (OFFICINA AROMATARIA) - CONCLUDED
• Essenza del territorio. Una rete per le vie sabaude dei profumi e dei sapori (LAGNASCO) - CONCLUDED
• EcoFood
• Genepì delle Alpi e altre piante officinali (ALCOTRA-GENEALP)
• Innovazione Tecnologica, Automazione e nuovi Controlli Analitici (ITACA)
• Monitoraggio esposizione a vegetali (POISON)

Activities in agenda

See my calendar

Academic bodies

• Commissione Passaggi Trasferimenti Riconoscimenti
• Consiglio di Dipartimento

• Commissione Monitoraggio e Riesame del corso di Laurea in Tecniche Erboristiche

Office hours

member of the board

member of tutors