Department of Drug Science and Technology

Research products

Selected research products

Squara S, Manig F, Henle T, Hellwig M, Caratti A, Bicchi C, Reichenbach SE, Tao Q, Collino M, Cordero C. (2023) Extending the breadth of saliva metabolome fingerprinting by smart template strategies and effective pattern realignment on comprehensive two-dimensional gas chromatographic data. Analytical and bioanalytical chemistry [DOI  PMID]

Caratti A, Squara S, Stilo F, Battaglino S, Liberto E, Cincera I, Genova G, Spigolon N, Bicchi C, Cordero C. (2022) Integrated Strategy for Informative Profiling and Accurate Quantification of Key-Volatiles in Dried Fruits and Nuts: An Industrial Quality Control Perspective. Foods (Basel, Switzerland) 11(19) [DOI  PMID]

Squara S, Ferrero F, Tabacco E, Cordero C, Borreani G. (2022) Effect of Inoculation with Lentilactobacillus buchneri and Lacticaseibacillus paracasei on the Maize Silage Volatilome: The Advantages of Advanced 2D-Chromatographic Fingerprinting Approaches. Journal of agricultural and food chemistry 70(38) 12232-12248 [DOI  PMID]

Strocchi G, Rubiolo P, Cordero C, Bicchi C, Liberto E. (2022) Acrylamide in coffee: What is known and what still needs to be explored. A review. Food chemistry 393 133406 [DOI  PMID]

Stilo F, Cialie Rosso M, Squara S, Bicchi C, Cordero C, Cagliero C. (2022) Corylus avellana L. Natural Signature: Chiral Recognition of Selected Informative Components in the Volatilome of High-Quality Hazelnuts. Frontiers in plant science 13 844711 [DOI  PMID]

Squara S, Stilo F, Cialie Rosso M, Liberto E, Spigolon N, Genova G, Castello G, Bicchi C, Cordero C. (2022) Corylus avellana L. Aroma Blueprint: Potent Odorants Signatures in the Volatilome of High Quality Hazelnuts. Frontiers in plant science 13 840028 [DOI  PMID]

Stilo F, Jimenez-Carvelo AM, Liberto E, Bicchi C, Reichenbach SE, Cuadros-Rodriguez L, Cordero C. (2021) Chromatographic Fingerprinting Enables Effective Discrimination and Identitation of High-Quality Italian Extra-Virgin Olive Oils. Journal of agricultural and food chemistry 69(31) 8874-8889 [DOI  PMID]

Stilo F, Segura Borrego MDP, Bicchi C, Battaglino S, Callejon Fernadez RM, Morales ML, Reichenbach SE, McCurry J, Peroni D, Cordero C. (2021) Delineating the extra-virgin olive oil aroma blueprint by multiple headspace solid phase microextraction and differential-flow modulated comprehensive two-dimensional gas chromatography. Journal of chromatography. A 1650 462232 [DOI  PMID]

Stilo F, Liberto E, Reichenbach SE, Tao Q, Bicchi C, Cordero C. (2021) Exploring the Extra-Virgin Olive Oil Volatilome by Adding Extra Dimensions to Comprehensive Two-Dimensional Gas Chromatography and Time-of-Flight Mass Spectrometry Featuring Tandem Ionization: Validation of Ripening Markers in Headspace Linearity Conditions. Journal of AOAC International 104(2) 274-287 [DOI  PMID]

Gabetti E, Sgorbini B, Stilo F, Bicchi C, Rubiolo P, Chialva F, Reichenbach SE, Bongiovanni V, Cordero C, Cavallero A. (2021) Chemical fingerprinting strategies based on comprehensive two-dimensional gas chromatography combined with gas chromatography-olfactometry to capture the unique signature of Piemonte peppermint essential oil (Mentha x piperita var Italo-Mitcham). Journal of chromatography. A 1645 462101 [DOI  PMID]

Cialie Rosso M, Stilo F, Mascrez S, Bicchi C, Purcaro G, Cordero C. (2021) Shelf-Life Evolution of the Fatty Acid Fingerprint in High-Quality Hazelnuts (Corylus avellana L.) Harvested in Different Geographical Regions. Foods (Basel, Switzerland) 10(3) [DOI  PMID]

Stilo F, Bicchi C, Reichenbach SE, Cordero C. (2021) Comprehensive two-dimensional gas chromatography as a boosting technology in food-omic investigations. Journal of separation science 44(8) 1592-1611 [DOI  PMID]

Cialie Rosso M, Stilo F, Squara S, Liberto E, Mai S, Mele C, Marzullo P, Aimaretti G, Reichenbach SE, Collino M, Bicchi C, Cordero C. (2021) Exploring extra dimensions to capture saliva metabolite fingerprints from metabolically healthy and unhealthy obese patients by comprehensive two-dimensional gas chromatography featuring Tandem Ionization mass spectrometry. Analytical and bioanalytical chemistry 413(2) 403-418 [DOI  PMID]

Stilo F, Liberto E, Spigolon N, Genova G, Rosso G, Fontana M, Reichenbach SE, Bicchi C, Cordero C. (2021) An effective chromatographic fingerprinting workflow based on comprehensive two-dimensional gas chromatography - Mass spectrometry to establish volatiles patterns discriminative of spoiled hazelnuts (Corylus avellana L.). Food chemistry 340 128135 [DOI  PMID]

Stilo F, Cordero C, Bicchi C, Peroni D, Tao Q, Reichenbach SE. (2020) Chromatographic Fingerprinting by Template Matching for Data Collected by Comprehensive Two-Dimensional Gas Chromatography. Journal of visualized experiments : JoVE (163) [DOI  PMID]

Stilo F, Gabetti E, Bicchi C, Carretta A, Peroni D, Reichenbach SE, Cordero C, McCurry J. (2020) A step forward in the equivalence between thermal and differential-flow modulated comprehensive two-dimensional gas chromatography methods. Journal of chromatography. A 1627 461396 [DOI  PMID]

Scavarda C, Cordero C, Strocchi G, Bortolini C, Bicchi C, Liberto E. (2021) Cocoa smoky off-flavour: A MS-based analytical decision maker for routine controls. Food chemistry 336 127691 [DOI  PMID]

Stilo F, Tredici G, Bicchi C, Robbat A Jr, Morimoto J, Cordero C. (2020) Climate and Processing Effects on Tea (Camellia sinensis L. Kuntze) Metabolome: Accurate Profiling and Fingerprinting by Comprehensive Two-Dimensional Gas Chromatography/Time-of-Flight Mass Spectrometry. Molecules (Basel, Switzerland) 25(10) [DOI  PMID]

Benetti E, Liberto E, Bressanello D, Bordano V, Rosa AC, Miglio G, Haxhi J, Pugliese G, Balducci S, Cordero C. (2020) Sedentariness and Urinary Metabolite Profile in Type 2 Diabetic Patients, a Cross-Sectional Study. Metabolites 10(5) [DOI  PMID]

Liberto E, Bressanello D, Strocchi G, Cordero C, Ruosi MR, Pellegrino G, Bicchi C, Sgorbini B. (2019) HS-SPME-MS-Enose Coupled with Chemometrics as an Analytical Decision Maker to Predict In-Cup Coffee Sensory Quality in Routine Controls: Possibilities and Limits. Molecules (Basel, Switzerland) 24(24) [DOI  PMID]

Spina F, Gea M, Bicchi C, Cordero C, Schiliro T, Varese GC. (2020) Ecofriendly laccases treatment to challenge micropollutants issue in municipal wastewaters. Environmental pollution (Barking, Essex : 1987) 257 113579 [DOI  PMID]

Rosso MC, Mazzucotelli M, Bicchi C, Charron M, Manini F, Menta R, Fontana M, Reichenbach SE, Cordero C. (2020) Adding extra-dimensions to hazelnuts primary metabolome fingerprinting by comprehensive two-dimensional gas chromatography combined with time-of-flight mass spectrometry featuring tandem ionization: Insights on the aroma potential. Journal of chromatography. A 1614 460739 [DOI  PMID]

Perotti P, Cordero C, Bortolini C, Rubiolo P, Bicchi C, Liberto E. (2020) Cocoa smoky off-flavor: Chemical characterization and objective evaluation for quality control. Food chemistry 309 125561 [DOI  PMID]

Morimoto J, Rosso MC, Kfoury N, Bicchi C, Cordero C, Robbat A Jr. (2019) Untargeted/Targeted 2D Gas Chromatography/Mass Spectrometry Detection of the Total Volatile Tea Metabolome. Molecules (Basel, Switzerland) 24(20) [DOI  PMID]

Stilo F, Liberto E, Reichenbach SE, Tao Q, Bicchi C, Cordero C. (2019) Untargeted and Targeted Fingerprinting of Extra Virgin Olive Oil Volatiles by Comprehensive Two-Dimensional Gas Chromatography with Mass Spectrometry: Challenges in Long-Term Studies. Journal of agricultural and food chemistry 67(18) 5289-5302 [DOI  PMID]

Cordero C, Guglielmetti A, Bicchi C, Liberto E, Baroux L, Merle P, Tao Q, Reichenbach SE. (2019) Comprehensive two-dimensional gas chromatography coupled with time of flight mass spectrometry featuring tandem ionization: Challenges and opportunities for accurate fingerprinting studies. Journal of chromatography. A 1597 132-141 [DOI  PMID]

Reichenbach SE, Zini CA, Nicolli KP, Welke JE, Cordero C, Tao Q. (2019) Benchmarking machine learning methods for comprehensive chemical fingerprinting and pattern recognition. Journal of chromatography. A 1595 158-167 [DOI  PMID]

Mack CI, Egert B, Liberto E, Weinert CH, Bub A, Hoffmann I, Bicchi C, Kulling SE, Cordero C. (2019) Robust Markers of Coffee Consumption Identified Among the Volatile Organic Compounds in Human Urine. Molecular nutrition & food research 63(10) e1801060 [DOI  PMID]

Sgorbini B, Cagliero C, Acquadro S, Marengo A, Cordero C, Liberto E, Bicchi C, Rubiolo P. (2019) Evaluation of volatile bioactive secondary metabolites transfer from medicinal and aromatic plants to herbal teas: Comparison of different methods for the determination of transfer rate and human intake. Journal of chromatography. A 1594 173-180 [DOI  PMID]

Cordero C, Guglielmetti A, Sgorbini B, Bicchi C, Allegrucci E, Gobino G, Baroux L, Merle P. (2019) Odorants quantitation in high-quality cocoa by multiple headspace solid phase micro-extraction: Adoption of FID-predicted response factors to extend method capabilities and information potential. Analytica chimica acta 1052 190-201 [DOI  PMID]

Sgorbini B, Cagliero C, Liberto E, Rubiolo P, Bicchi C, Cordero C. (2019) Strategies for Accurate Quantitation of Volatiles from Foods and Plant-Origin Materials: A Challenging Task. Journal of agricultural and food chemistry 67(6) 1619-1630 [DOI  PMID]

Liberto E, Cordero C, Bicchi C. (2019) 4(th) Conference on Cocoa Coffee and Tea (CoCoTea 2017) - The world in a cup. Food research international (Ottawa, Ont.) 115 302 [DOI  PMID]

Giardina M, McCurry JD, Cardinael P, Semard-Jousset G, Cordero C, Bicchi C. (2018) Development and validation of a pneumatic model for the reversed-flow differential flow modulator for comprehensive two-dimensional gas chromatography. Journal of chromatography. A 1577 72-81 [DOI  PMID]

Ulaszewska MM, Weinert CH, Trimigno A, Portmann R, Andres Lacueva C, Badertscher R, Brennan L, Brunius C, Bub A, Capozzi F, Cialie Rosso M, Cordero CE, Daniel H, Durand S, Egert B, Ferrario PG, Feskens EJM, Franceschi P, Garcia-Aloy M, Giacomoni F, Giesbertz P, Gonzalez-Dominguez R, Hanhineva K, Hemeryck LY, Kopka J, Kulling SE, Llorach R, Manach C, Mattivi F, Migne C, Munger LH, Ott B, Picone G, Pimentel G, Pujos-Guillot E, Riccadonna S, Rist MJ, Rombouts C, Rubert J, Skurk T, Sri Harsha PSC, Van Meulebroek L, Vanhaecke L, Vazquez-Fresno R, Wishart D, Vergeres G. (2019) Nutrimetabolomics: An Integrative Action for Metabolomic Analyses in Human Nutritional Studies. Molecular nutrition & food research 63(1) e1800384 [DOI  PMID]

Bressanello D, Liberto E, Cordero C, Sgorbini B, Rubiolo P, Pellegrino G, Ruosi MR, Bicchi C. (2018) Chemometric Modeling of Coffee Sensory Notes through Their Chemical Signatures: Potential and Limits in Defining an Analytical Tool for Quality Control. Journal of agricultural and food chemistry 66(27) 7096-7109 [DOI  PMID]

Mastrocola R, Ferrocino I, Liberto E, Chiazza F, Cento AS, Collotta D, Querio G, Nigro D, Bitonto V, Cutrin JC, Rantsiou K, Durante M, Masini E, Aragno M, Cordero C, Cocolin L, Collino M. (2018) Fructose liquid and solid formulations differently affect gut integrity, microbiota composition and related liver toxicity: a comparative in vivo study. The Journal of nutritional biochemistry 55 185-199 [DOI  PMID]

Bressanello D, Liberto E, Collino M, Chiazza F, Mastrocola R, Reichenbach SE, Bicchi C, Cordero C. (2018) Combined untargeted and targeted fingerprinting by comprehensive two-dimensional gas chromatography: revealing fructose-induced changes in mice urinary metabolic signatures. Analytical and bioanalytical chemistry 410(11) 2723-2737 [DOI  PMID]

Cagliero C, Bicchi C, Cordero C, Liberto E, Rubiolo P, Sgorbini B. (2018) Ionic liquids as water-compatible GC stationary phases for the analysis of fragrances and essential oils. Analytical and bioanalytical chemistry 410(19) 4657-4668 [DOI  PMID]

Rosso MC, Liberto E, Spigolon N, Fontana M, Somenzi M, Bicchi C, Cordero C. (2018) Evolution of potent odorants within the volatile metabolome of high-quality hazelnuts (Corylus avellana L.): evaluation by comprehensive two-dimensional gas chromatography coupled with mass spectrometry. Analytical and bioanalytical chemistry 410(15) 3491-3506 [DOI  PMID]

Courses

• : Advances in food metabolomics
  Dottorato in Scienze Farmaceutiche e Biomolecolari
• Alimenti (SSP 0005)
  Corso di Laurea in Tecniche della Prevenzione nell'Ambiente e nei Luoghi di Lavoro - SNT/4
• CHIMICA DEGLI ALIMENTI A.A. 2021-2022 (MFN1405)
  Corso di laurea in Chimica e Tecnologie Chimiche
• CHIMICA E MERCEOLOGIA DEGLI ALIMENTI (MED3230)
  Corso di Laurea in Dietistica
• Chimica degli Alimenti (MED3230A)
  Corso di Laurea in Dietistica
• Chimica degli Alimenti (SSFO) (STF0134)
  Corsi di studio in
  Farmacia - Chimica e tecnologia farmaceutiche
• Chimica degli alimenti (CTF) (STF0007)
  Corsi di studio in
  Farmacia - Chimica e tecnologia farmaceutiche
• Chimica degli alimenti e dei prodotti dietetici (Tecniche erboristiche) (FAR0255)
  Corso di Laurea in Tecniche Erboristiche
• Controllo analitico di residui e contaminanti per la prevenzione dei rischi alimentari (SSP0005A)
  Corso di Laurea in Tecniche della Prevenzione nell'Ambiente e nei Luoghi di Lavoro - SNT/4
• Dietary supplements and functional foods (---)
  Master di II livello in "Innovation in Food Science and Technology – Michele Ferrero"
• Food Chemistry (---)
  Master di II livello in "Innovation in Food Science and Technology – Michele Ferrero"
• Food safety and Security (STF0281)
  Corsi di studio in
  Farmacia - Chimica e tecnologia farmaceutiche
• Integrated Course - Chemical and Microbiological Indexes for Quality and Safety of Foods
  Master di II livello in "Innovation in Food Science and Technology – Michele Ferrero"
• Sensory analysis I (---)
  Master di II livello in "Innovation in Food Science and Technology – Michele Ferrero"
• Sensory analysis II (---)
  Master di II livello in "Innovation in Food Science and Technology – Michele Ferrero"
• Technology Innovation
  Dottorato in Scienze Farmaceutiche e Biomolecolari

Research topics

Research groups

• Pharmaceutical Biology and Food Chemistry
• Food Chemistry (FOODCHEM)

Research projects

• MILK-ZERO Effetti della gestione delle produzioni nell'azienda zootecnica sulla presenza di contaminanti nei prodotti lattiero-caseari: Studio di una filiera a residuo zero in Piemonte
• NUTRAcore Piattattaforma integrata per lo sviluppo di processi innovativi
• Valorization of Italian Olive products through Innovative analytical tools - VIOLIN
• Valorization of Italian OLive products through INnovative analytical tools- VIOLIN
• Essenza del Territorio (OFFICINA AROMATARIA) - CONCLUDED
• Essenza del territorio. Una rete per le vie sabaude dei profumi e dei sapori (LAGNASCO) - CONCLUDED
• EcoFood
• Genepì delle Alpi e altre piante officinali (ALCOTRA-GENEALP)
• Innovazione Tecnologica, Automazione e nuovi Controlli Analitici (ITACA)
• Monitoraggio esposizione a vegetali (POISON)

Academic bodies

• Commissione Didattica
• Consiglio di Dipartimento

Office hours

member of tutors